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News - Prostate Cancer

Articles and Reports - Table of Contents
Links to Original Articles and Reports

Avoiding the Prostate Cancer Treatment Nightmare

Most men are totally unaware and unconcerned about their prostate gland it—until it starts giving them problems. What happens next..............

To PSA or Not to PSA: A Guide for the Over Fifty Male

A discussion of the results of the May 2012, the U.S. Preventative Services Task Force recommendation against routine PSA testing as a screen for prostate cancer.

PSA test distress, study urges caution

Research has brought out that the prostate cancer tests can cause significant psychological distress to the men undergoing the screening.

New PSA Test Improves Detection of Prostate Cancer

Testing for the (-2)-isoform of proenzyme prostate specific antigen (p2PSA) is more accurate than PSA testing in differentiating prostate cancer from benign disease, according to a report in the April 2010 issue of The Journal of Urology.

Over A Million Men Overdiagnosed for Prostate Cancer, Treated Unnecessarily

Since the prostate antigen screening test (PSA) began being widely used about 23 years ago, doctors have lauded its ability to detect prostate cancer at a very early stage. In fact, PSA testing has resulted in over a million additional men being diagnosed and treated for prostate cancer. The problem is, according to new research just published online in the Journal of the National Cancer Institute, most of these cases were over-diagnosed and subjected men to treatment they didn't need.

Risk of suicide and heart attacks goes up when men are told they have prostate cancer

Imagine you are a man who has just been told you have a disease that might kill you -- prostate cancer. And the treatment may involve surgery, chemotherapy, radiation and/or hormones that could rob you of your virility, wreck your sex life...

Can Drugs Really prevent Prostate Cancer?

If you worry about getting prostate cancer, you would have to live on another planet to be unaware of the hype surrounding the use of prescription drugs like dutasteride (Avodart) or finasteride (Proscar) for preventing prostate cancer. This article explores the truth behind the hype.

Watchful Waiting — An Accident Waiting to Happen?

"Watchful Waiting" and "Active Surveillance" are equivalent terms used to describe an option sometimes offered to men with "low-grade" or "favorable-risk" prostate cancer in lieu of more immediate, aggressive treatment. Unfortunately, most men are rarely advised about natural techniques that may help reduce or slow the growth of their prostate cancer.

Preliminary SELECT Study Results are Misleading!
by James Occhiogrosso, N.D., Nov. 3, 2008

In Oct. 2008 the National Cancer Institute (NCI) released preliminary results from the ongoing SELECT trial that stated that vitamin E and selenium do not protect against prostate cancer.  Study participants are being sent a letter that explains these initial preliminary results and tells them to stop taking their study supplements.

Natural Vitamin E, Selenium, Zinc and Prostate Health - by James Occhiogrosso, N.D., Nov. 3, 2008

This article is a condensation of several pages from my book about natural vitamin E, selenium and zinc. These three substances work synergistically to improve prostate health.

NCI's Flawed SELECT Study Attacks Vitamin E
by Byron Richards, October 30 2008

The National Cancer Institute's (NCI) SELECT study (Selenium and Vitamin E Cancer Prevention ­Trial) for prostate cancer in men was halted this week after initial data analysis showed that selenium and vitamin E, taken alone or together for an average of five years, did not prevent prostate cancer. 

Preliminary SELECT Results - Press Release
National Cancer Institute, Oct. 2008

Selenium and vitamin E supplements, taken either alone or together, did not prevent prostate cancer. Because this is an early analysis of the data from the study, neither of these findings proves an increased risk from the supplements and both may be due to chance. 

Systematic Review: Comparative Effectiveness and Harms of Treatments for Clinically Localized Prostate Cancer,  Timothy J. Wilt, M.D., et al, Annuls of Internal medicine, March 2008, Volume 148, Issue 6, Pages 435-448

The link above is to the full text of this study. It is hard to believe that for an illness that effects several hundred thousand men per year, there is so little concrete evidence to guide treatment decisions. This study is a technical review of the treatment strategies from nearly 500 different studies.   

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Prevalence of incidental prostate cancer in the general population: a study of healthy organ donors
Journal of Urology, March 2008, Vol. 179, No. 3, pgs. 892-5
by: Yin M, Bastacky S, Chandran U, Becich MJ, Dhir R. 

This links to an abstract which supports the next few articles. It is a study of 340 men with no history of prostate disease that died from various and were organ donors. The study found approximately a 30% chance of having incidental cancer in the 60 to 69-year-old age group increasing to 46% of 70 to 81-year-old men. 

Is it safe delaying decision about having prostate cancer surgery? Men's Health News, Friday, 8-Feb-2008

Is it safe to wait to make a decision about having prostate cancer surgery, or will the additional delay reduce your chances of being cured?  Reassuring research says that men can take the time they need to make their decisions, reports the February 2008 issue of Harvard Men's Health Watch.

Comment: As I mention several times in my book "Your Prostate, Your Libido, Your Life" - many men panic at a cancer diagnosis and opt for immediate treatment without a through evaluation of their options.  Most aggressive treatments have significant side effects and cannot be undone, no matter how much one later regrets it!

Effects of prostate removal
Men's Health News, Monday, 4-Feb-2008

Men with prostate cancer who have their prostate removed cite sexual dysfunction as the most common side effect after surgery, but urinary dysfunction troubles these patients most, reports a University of Florida researcher. What's more, many aren't emotionally prepared to face these complications.

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Prostate Cancer: Treatment or Overtreatment?
By James Occhiogrosso, N.D., Jan. 26, 2008

This article discusses why so many men with localized, low-risk, prostate cancer choose aggressive treatment instead of a watchful waiting approach.

Comparative Effectiveness and Harms of Treatments for Clinically Localized Prostate Cancer
Annuls of Internal Medicine, March 2008, Wilt, T., MD, et al 

Comment: The link above is the full text of this report. Below is the first paragraph of its discussion section. Any man considering treatment may want to read this entire report and discuss it with his clinician prior to making a treatment decision.

Little high-quality evidence is available to guide patients and their families and health care providers on the comparative effectiveness and harms of treatments for clinically localized prostate cancer, especially in men with PSA-detected disease. Because the quality of evidence on treatment effectiveness, necessity, and harm was limited, we could not accurately assess many clinically important outcomes. All treatments cause adverse events (primarily urinary, bowel, and sexual) that occur soon after therapy, although the frequency, duration, and severity vary among treatments.

Androgen Deprivation Therapy for Localized Prostate Cancer and the Risk of Cardiovascular Mortality
Journal of the Nat. Cancer Institute, Oct. 2007, Tsai, H., et al.

The use of ADT appears to be associated with an increased risk of death from cardiovascular causes in patients undergoing radical prostatectomy for localized prostate cancer.

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Prostate cancer treatment may encourage spread of cancer cells -- Men's Health News, Oct. 2007

According to a new study by researchers in the U.S. the popular prostate cancer treatment, androgen deprivation therapy, may in fact encourage the spread of cancer cells throughout the body. The treatment 'androgen deprivation therapy' (ADT), is not considered to be a cure but is thought to delay the growth and spread of tumors which are inoperable. However this new research suggests that the therapy encourages the production of a protein that makes the cancer cells more likely to proliferate.

Prostate Cancer Treatments Yield Different Quality of Life Outcomes.  NEW YORK (Reuters Health) Jun 07, 2007

In making decisions about treatment, men with prostate cancer should take into consideration the fact that surgery, external beam radiation therapy, and brachytherapy for early-stage prostate cancer yield different quality of life outcomes, according to a report in the June 1st issue of Cancer.

Shark Cartilage Extract Has No Effect in Cancer
Medscape Medical News, Zosia Chustecka, June 6, 2007

(Chicago) — Shark cartilage, marketed as an "alternative medicine" for use in cancer, was shown to have no effect in a large phase 3 study sponsored by the National Cancer Institute (NCI). The supplement was added to treatment with chemoradiation in patients with non–small-cell lung cancer (NSCLC) and was shown to have no effect on survival when compared with placebo.

Comment: While this study does not specifically address prostate cancer, its posted here because I have had numerous folks ask about shark cartilage.  I have never seen any science that would lead me to believe shark cartilage has any benefit for prostate cancer or any other cancer.

Red wine protects men from prostate cancer
Men's Health News Published: Wednesday, 23-May-2007

Researchers have found that men who drink an average of four to seven glasses of red wine per week are only 52% as likely to be diagnosed with prostate cancer as those who do not drink red wine, reports the June 2007 issue of Harvard Men's Health Watch. In addition, red wine appears particularly protective against advanced or aggressive cancers.

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Taking too many multivitamins may be linked to advanced prostate cancer.
Men's Health News Published: Wednesday, 16-May-2007

While regular multivitamin use is not linked with early or localized prostate cancer, taking too many multivitamins may be associated with an increased risk for advanced or fatal prostate cancers, according to a study in the May 16 issue of the Journal of the National Cancer Institute.

Comment: — Studies like this scare people and make great headlines. Often, they are taken out of context or are simply poor or biased science. To the credit of the authors of this study, they comment “uncontrolled factors in a study of this type may obscure the true relationship between multivitamin use and prostate cancer.”

One uncontrolled factor is that men with a family history of prostate cancer, as indicated in the study, often take higher doses of many nutrients in an attempt to head off their familial predisposition to the disease. That such men have a higher incidence of prostate cancer is certainly no surprise and likely relates more to their genetic makeup than to whether or not they are taking excessive multivitamins. Stories like these make great headlines, but I will keep taking my vitamins and minerals.

Unfortunately, what didn't make headlines in this study was that it also concluded that there was no increase in the overall incidence of prostate cancer among the vitamin taking group.

New Prostate Cancer Blood Test Shows Promise.
Journal of Urology -Jan. 2008

Testing for a blood protein researchers are calling early prostate cancer antigen (EPCA)-2 may overcome some of the limitations of current practices. While screening for prostate-specific antigen (PSA) has been the standard of care for more than 2 decades, it is not specific for prostate cancer, and raised concentrations have been linked to other prostate conditions such as benign prostatic hyperplasia and prostatitis. Several groups have been working to identify new biomarkers for prostate cancer, and this latest effort, published in the April issue of Urology, shows that EPCA-2 has potential as a new serum-based test.

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After a cancer diagnosis: Crucial questions to consider about chemotherapy vs. naturopathic cancer treatments.
NaturalNews.com, Thursday, April 26, 2007 by: Mike Adams

It is widely known that an increasing number of consumers are turning to alternative medicine for treatment for diseases like cancer, depression, diabetes, heart disease and so on. What are generally not known are the circumstances under which many consumers make this switch from conventional to alternative medicine.

The top five cancer-causing foods.
NaturalNews.com, Tuesday, April 24, 2007 by: Mike Adams

Ever wonder which foods should be strongly avoided by those at high risk for cancer? We can begin identifying cancer-causing foods once we know which ingredients in our food cause cancer. Some of those ingredients are food additives and chemicals used to enhance taste, while others are used strictly for appearance or to increase product shelf life. The key to avoiding cancer-causing foods is knowing which ingredients are carcinogens -- or cancer promoters -- and then reading food labels to permanently avoid consuming those ingredients.

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Smoking associated with worse outcomes in patients with prostate cancer treated by radical radiotherapy.
Men's Health News, Published: Friday, 20-Apr-2007

A history of smoking is associated with an increased risk of metastatic disease in patients treated with radiotherapy (XRT) for prostate cancer (CaP), according to a report in the online version of the BJU International.

Prostate cancer treatment decisions can be complicated.
Men's Health News, Published: Friday, 20-Apr-2007

For many men with early-stage prostate cancer, sorting out the treatment options can be overwhelming. Yet they feel pressured to choose a course of therapy quickly. The first issue of a new quarterly bulletin about prostate disease published by Harvard Medical School says that the most important thing to do is to take your time and make sure you explore all treatment choices thoroughly.

Comment: - This concept cannot be emphasized enough.  Exploring treatment choices can save you from unnecessary and possibly debilitating consequences!

Obesity at the time of prostate-cancer diagnosis dramatically increases the risk of dying from the disease.
Source: News-Medical.Net, Published: Thursday, 15-Mar-2007

Obese men who are diagnosed with prostate cancer have more than two-and-a-half times the risk of dying from the disease as compared to men of normal weight at the time of diagnosis, according to a study by researchers at Fred Hutchinson Cancer Research Center.

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For prostate cancer, doing nothing is often just as good as seeking immediate treatment.
NaturalNews.com — March 12, 2007 by: David Gutierrez

In many lower-risk cases of prostate cancer, men actually may place their health at greater risk by treating the cancer than by waiting and monitoring it, according to many doctors. But a new study by Dr. Daniel Barocas, chief resident in your Rolla G. at New York Presbyterian Hospital-Weill Cornell Medical College, suggests that few men are comfortable with this hands-off approach.

Comment at bottom of page

Active Surveillance Underutilized in Prostate Cancer. 
Medscape Medical News, Mar. 2, 2007, By: Zosia Chustecka  

Only about half of the men with prostate cancer who have low-risk disease choose to be followed with active surveillance, or "watchful waiting," instead of opting for immediate treatment. "Our findings suggest that active surveillance is an underutilized strategy for managing patients with very low-risk prostate cancer," said lead researcher Daniel Barocas, MD, from New York Presbyterian Hospital and Weill Medical College of Cornell University, in New York. "Patients should talk to their doctors about their risk category and whether they are appropriate candidates for this approach."

Comment at bottom of page

With some prostate cases, wait-and-see may be best approach, study finds.
From: USA TODAY By: Liz Szabo, February 23, 2007

ORLANDO — When faced with a diagnosis of prostate cancer, the vast majority of men opt to treat the disease, including those who might benefit from a wait-and-see approach that spares them from long-term side effects of surgery or radiation, a small new study shows.

Comment: As I strongly state in my book, "Your Prostate, Your Libido, Your Life", I do not consider watchful waiting (where you regularly have a rectal exam and test your PSA), a viable option unless you are actively taking steps to improve your condition naturally. 

While testing regularly is of value, in my opinion it is critically important to get the proper nutritional and herbal elements into your body to help it fight the cancer during this period.  It is at this time - when the condition is minimal - that natural techniques stand the best chance of helping.

Waiting and doing nothing more than regular testing is essentially waiting for your condition to get bad enough to warrant more  aggressive conventional treatment! Improving prostate health with natural products and techniques while you regularly get examined and tested by your doctor may prevent disease progression and unnecessary grief!


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